Preparation for MR analysis via BrainVoyager

Back-up your Raw Data before doing any process!

The following steps are the protocol which I used for my data analysis. Any other experiment or experimental process may require rearrangements on this protocol. I am trying to help for operating the fMRI data analysis via BrainVoyager; however, think wisely for your own analysis. Reading the UserGuide is highly recommended.

1. CREATE VMR FILE

Follow the steps of “New Doc Wizard”.

Use data from T1-weighted scan.

naming: Subject.vmr

2. ACPC AND TAL TRANSFORMATION

Volumes –> 3D Volume Tools –> Talairach

Under “ACPC Transformation” part
– press the “Detect MSP, AC, PC”
– press the “Transform to ACPC”
Under “Specification and visualization of Talairach landmarks”
– press the “Save .TAL…”
– press “ACPC –> TAL…q”

3. SEGMENTATION

Volumes –> 3D Volume Tools –> Segmentation

Press the “Autom. Segm.” button.

4. MESH MORPHING

Meshes –> Mesh Morphing

Inflation mode is on.

5. SMOOTH MESH

Meshes –> Background and Curvate Colors

3 times “Smooth” the mesh

6. CREATE FMR FILE

Follow the steps of “New Doc Wizard”.

Create FMR files for each functional scan.

naming: Subject_Condition.fmr

7. FMR PREPROCESSING

Analysis –> FMR Preprocessing

Slice-Scan Time Correction, Temporal Filtering and 3D Motion Correction is applied.

  • To apply intra-session alignment:
    Advanced –> 3D motion correction Options –> “Select the FMR file for the first run as reference file”

8. FMR-VMR COREGISTRATION

While Subject.vmr is open, go to 3D Volume Tools –> Coregistration.

“Select FMR…” and press the “Align”.

First proceed Initial Alignment. If the result seems to be appropriate, run Final Alignment.

9. CREATE VTC FILE

Go to Analysis –> Create Normalized VTC from FMR Data

Select the files required for the relative parts.

Select ACPC at the top bar. Then, add ACPC.trf 

10. CREATE PNG FILES FOR EACH FRAME

If you are performing pRF estimation, you need to have screenshots of each frame presented during each volume of TR. The saved PNG files are required to be:

  • binary (0 and 1 or black and white)
  • 150px * 150px in size

You can save each frame via the tool you are using for stimulus presentation.

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